pentobarbital will minimize the level or result of montelukast by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.
pentobarbital will lower the level or impact of repaglinide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will reduce the extent or impact of fruquintinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. If coadministration with reasonable CYP3A4 inducers is unavoidable, continue to administer fruquintinib at proposed dosage.
Contraindicated (1)pentobarbital will lower the extent or result of cobimetinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Stay away from coadministration. Sturdy or reasonable CYP3A inducers may lower cobimetinib systemic exposure by >80% and cut down its efficacy.
pentobarbital will reduce the extent or result of conjugated estrogens by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
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Adhering to oral or parenteral administration, barbiturates quickly cross the placental barrier and therefore are dispersed throughout fetal tissues with maximum concentrations located in the placenta, fetal liver, and brain; fetal blood degrees approach maternal blood stages next parenteral administration
Keep an eye on Intently (one)pentobarbital will lessen the extent or effect of tofacitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. Loss of, or lowered response to tofacitinib might happen when coadministered with powerful CYP3A4 inducers
pentobarbital will lower the extent or effect of trazodone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
Observe Intently (2)pentobarbital will minimize the extent or influence of diazepam intranasal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Sturdy or average CYP3A4 inducers may perhaps increase level of diazepam elimination; for that reason, efficacy of diazepam may very well be lessened.
pentobarbital will decrease the click here extent or impact of indinavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
Contraindicated (1)pentobarbital will lower the extent or outcome of naloxegol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Usage of naloxegol with potent CYP3A4 inducers just isn't proposed
pentobarbital will raise the amount or impact of clopidogrel by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will minimize the level or influence of levamlodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.